3-Diaminobenzoic acid
2,3-Diaminobenzoic acid
CAS: 603-81-6
Molecular Formula: C7H8N2O2
3-Diaminobenzoic acid - Names and Identifiers
| Name | 2,3-Diaminobenzoic acid |
| Synonyms | 3-Diaminobenzoic acid 2,3-Diaminobenzonicacid 2,3-Diaminobenzoic acid 2,3-DIAMINOBENZOIC ACID Benzoic acid,2,3-diamino- Benzoic acid, 2,3-diamino- 2,3-bis(azanyl)benzoic acid 3-carboxy-1,2-diaminobenzene 2,3-diaMinobenzoic acid hydrochloride |
| CAS | 603-81-6 |
| InChI | InChI=1/C7H8N2O2/c8-5-3-1-2-4(6(5)9)7(10)11/h1-3H,8-9H2,(H,10,11) |
3-Diaminobenzoic acid - Physico-chemical Properties
| Molecular Formula | C7H8N2O2 |
| Molar Mass | 152.15 |
| Density | 1.2804 (rough estimate) |
| Melting Point | 198-204 °C |
| Boling Point | 274.61°C (rough estimate) |
| Flash Point | 185.3°C |
| Vapor Presure | 1.53E-06mmHg at 25°C |
| pKa | 5.10±0.10(Predicted) |
| Storage Condition | Keep in dark place,Inert atmosphere,Room temperature |
| Refractive Index | 1.5200 (estimate) |
3-Diaminobenzoic acid - Risk and Safety
| Risk Codes | R22 - Harmful if swallowed R36 - Irritating to the eyes |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| HS Code | 29224999 |
| Hazard Class | IRRITANT |
3-Diaminobenzoic acid - Introduction
2,3-Diaminobenzoic acid is an organic compound with the chemical formula C7H8N2O2. The following is information about the properties, uses, preparation and safety of 2,3-diaminobenzoic acid:
Nature:
-Appearance: 2,3-Diaminobenzoic acid is a white crystalline solid.
-Solubility: It is soluble in water, alcohol and acidic solution.
-Melting point: The melting point of 2,3-diaminobenzoic acid is 215-218°C.
-Chemical properties: It is a compound with two amino groups and one carboxyl group, which can be used as a reactant for acids and bases.
Use:
-Chemical synthesis: 2,3-Diaminobenzoic acid can be used as raw materials and intermediates in organic synthesis, and is often used in the synthesis of other organic compounds.
-Dye: It can be used as a synthetic component of chemical dyes and pigments.
-Drugs: 2,3-diaminobenzoic acid can also be used in the synthesis of certain drugs.
-Biochemical research: In biochemical research, it can be used to prepare DNA labeling reagents and chromogenic reagents.
Preparation Method:
There are two main methods for the preparation of 2,3-diaminobenzoic acid:
1. by reacting aniline with phthalic anhydride. First, aniline is condensed with ammonia and aldehyde to obtain 2,3-diaminobenzaldehyde, and then reacted with acid anhydride to obtain the target product 2,3-diaminobenzoic acid.
2. It can be obtained by meta-isomerization or reduction reaction of p-aniline and o-nitrobenzoic acid.
Safety Information:
- 2,3-Diaminobenzoic acid has low toxicity, but it still needs to be used carefully.
-When in contact with the skin, it may cause irritation. It is recommended to wear protective gloves during operation.
-If ingested or inhaled, seek medical attention immediately.
-During storage and use, avoid contact with oxidants and strong acids to avoid dangerous reactions.
Please note that before using and operating 2,3-diaminobenzoic acid, you should fully understand the relevant safety information and follow the relevant safety operating procedures.
Nature:
-Appearance: 2,3-Diaminobenzoic acid is a white crystalline solid.
-Solubility: It is soluble in water, alcohol and acidic solution.
-Melting point: The melting point of 2,3-diaminobenzoic acid is 215-218°C.
-Chemical properties: It is a compound with two amino groups and one carboxyl group, which can be used as a reactant for acids and bases.
Use:
-Chemical synthesis: 2,3-Diaminobenzoic acid can be used as raw materials and intermediates in organic synthesis, and is often used in the synthesis of other organic compounds.
-Dye: It can be used as a synthetic component of chemical dyes and pigments.
-Drugs: 2,3-diaminobenzoic acid can also be used in the synthesis of certain drugs.
-Biochemical research: In biochemical research, it can be used to prepare DNA labeling reagents and chromogenic reagents.
Preparation Method:
There are two main methods for the preparation of 2,3-diaminobenzoic acid:
1. by reacting aniline with phthalic anhydride. First, aniline is condensed with ammonia and aldehyde to obtain 2,3-diaminobenzaldehyde, and then reacted with acid anhydride to obtain the target product 2,3-diaminobenzoic acid.
2. It can be obtained by meta-isomerization or reduction reaction of p-aniline and o-nitrobenzoic acid.
Safety Information:
- 2,3-Diaminobenzoic acid has low toxicity, but it still needs to be used carefully.
-When in contact with the skin, it may cause irritation. It is recommended to wear protective gloves during operation.
-If ingested or inhaled, seek medical attention immediately.
-During storage and use, avoid contact with oxidants and strong acids to avoid dangerous reactions.
Please note that before using and operating 2,3-diaminobenzoic acid, you should fully understand the relevant safety information and follow the relevant safety operating procedures.
Last Update：2024-04-09 15:17:58
